PT  - JOURNAL ARTICLE
AU  - Hoyle, Brian
ED  - Webster, Lynn
TI  - Naldemedine Effective at Relieving Opioid-Induced Constipation
DP  - 2015 Sep 07
TA  - MD Conference Express
PG  - 11--11
VI  - 15
IP  - 14
4099  - http://mdc.sagepub.com/content/15/14/11.short
4100  - http://mdc.sagepub.com/content/15/14/11.full
AB  - A phase 2b randomized, double-blind, placebo-controlled study shows that naldemedine, a peripherally acting µ-opioid receptor antagonist, is effective in easing opioid-induced constipation compared to placebo. Phase 3 development is expected for the 0.2 mg/day naldemedine dose.