PT  - JOURNAL ARTICLE
AU  - Summers, Jaye
ED  - Reau, Nancy
TI  - Analysis of SVR Rates Across Populations With Multiple Negative Predictors
DP  - 2015 Sep 07
TA  - MD Conference Express
PG  - 8--9
VI  - 15
IP  - 14
4099  - http://mdc.sagepub.com/content/15/14/8.short
4100  - http://mdc.sagepub.com/content/15/14/8.full
AB  - Multivariate analysis shows that > 2000 patients with hepatitis C virus who received 3 direct-acting antivirals and had <4 predictors of negative response experienced 12-week sustained virologic response rates > 95%. Analysis of those that received the label-recommended regimen found that the only 2 negative predictors associated with significantly lower response rates are obesity and genotype 1a disease. Even those with both factors achieved sustained virologic response rates of 95% at week 12.