Summary
Agents that reverse the effect of vitamin K antagonists include plasma, vitamin K, and prothrombin complex concentrate. Hemostasis is most likely to be achieved by using a prothrombin complex concentrate. Guidelines for reversing the effect of direct-acting anticoagulants are based on guidelines that reflect the paucity of high-quality evidence.
- warfarin
- direct-acting anticoagulants
- vitamin K antagonists
- vitamin K
- plasma
- prothrombin complex concentrate
- rivaroxaban
- edoxaban
- dabigatran
- apixaban
- reversal
- cardiology & cardiovascular medicine clinical trials
- cardiology & cardiovascular medicine guidelines
- © 2015 SAGE Publications
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