MINT=myocardial infarction with novastan and t-PA; t-PA=tissue plasminogen activator; TIMI 3= thrombolysis in myocardial infarction grade 3 flow.Reproduced from Jang IK et al. A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (t-PA) in acute myocardial infarction: myocardial infarction with novastan and t-PA (MINT) study. J Am Coll Cardiol 1997; 33(7):1879–1885. With permission from Elsevier.
Incidence of ICH, Recanalization, and Reocclusion in ARTSS-1
ICH=intracranial hemorrhage; PH-2=parenchymal hemorrhage type-2; t-PA=tissue plasminogen activator. tPA-alone historical controls were prospectively planned and obtained from the CLOTBUST study [Alexandrov AV et al. N Engl J Med 2004].Reproduced with permission from AD Barreto, MD.