RT Journal Article
SR Electronic
A1 Mosley, Mary
T1 Blood Pressure Variability after ICH Predicts Poor Outcomes
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 1
SP 17
OP 18
DO 10.1177/155989771401011
UL http://mdc.sagepub.com/content/14/1/17.abstract
AB The Second Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial [INTERACT2; Anderson CS et al. N Engl J Med 2013] showed that early, target-driven (<140 mm Hg) lowering of systolic blood pressure (SBP) was safe and improved functional outcomes compared with guideline-directed BP management (SBP, <180 mm Hg). A post hoc analysis has now shown that within individual variability in SBP during the first 24 hours and days 2 to 7 following acute intracerebral hemorrhage (ICH) predicts outcome [Manning L et al. Lancet Neurol 2014].