RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 Survival Benefit of rt-PA Not Affected by Age When Delivered up to 4.5 Hours Post Event
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 1
SP 11
OP 11
DO 10.1177/155989771401004
UL http://mdc.sagepub.com/content/14/1/11.1.abstract
AB Intravenous recombinant tissue plasminogen activator (rt-PA) is effective in the treatment of acute ischemic stroke; however, there has been some doubt regarding the timing of its use, its use in older patients, as well as its use in patients with different levels of stroke severity. This article presents data indicating that regardless of patient age, rt-PA improves the odds of surviving with no significant disability when delivered within 4.5 hours of stroke onset, with earlier treatment leading to proportionally bigger benefit.