PT - JOURNAL ARTICLE AU - Cunningham, Muriel ED - Shahzad, Adeel TI - Single-Center Study Finds Bivalirudin Associated with Increased Ischemic Risk in Primary PCI for STEMI (HEAT PPCI) DP - 2014 Jun 01 TA - MD Conference Express PG - 26--27 VI - 14 IP - 4 4099 - http://mdc.sagepub.com/content/14/4/26.short 4100 - http://mdc.sagepub.com/content/14/4/26.full AB - This article presents results from the How Effective Are Antithrombotic Therapies in Primary Percutaneous Coronary Intervention trial [HEAT PPCI; NCT01519518]. All patients with ST-segment elevation myocardial infarction presenting at a single United Kingdom center were randomized to open-label treatment with heparin (70 units/kg body weight preprocedure) or bivalirudin (bolus of 0.75 mg/kg followed by 1.75 mg/kg/hour infusion during the procedure) on top of preprocedure dual antiplatelet therapy.