RT Journal Article
SR Electronic
A1 Hoyle, Brian
T1 Methylprednisolone Not Beneficial in High-Risk Cardiac Surgery Patients (SIRS)
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 4
SP 23
OP 24
DO 10.1177/155989771404013
UL http://mdc.sagepub.com/content/14/4/23.abstract
AB This article discusses the findings of the Steroids in Cardiac Surgery Trial [SIRS Trial; NCT00427388]. Inflammation triggered by cardiopulmonary bypass can be diminished using prophylactic steroids, which may produce clinical benefits. The SIRS trial assessed the hypothesis of whether methylprednisolone would reduce perioperative adverse events in high-risk patients undergoing cardiac surgery involving cardiopulmonary bypass.