PT  - JOURNAL ARTICLE
AU  - Hoyle, Brian
ED  - Whitlock, Richard
TI  - Methylprednisolone Not Beneficial in High-Risk Cardiac Surgery Patients (SIRS)
DP  - 2014 Jun 01
TA  - MD Conference Express
PG  - 23--24
VI  - 14
IP  - 4
4099  - http://mdc.sagepub.com/content/14/4/23.short
4100  - http://mdc.sagepub.com/content/14/4/23.full
AB  - This article discusses the findings of the Steroids in Cardiac Surgery Trial [SIRS Trial; NCT00427388]. Inflammation triggered by cardiopulmonary bypass can be diminished using prophylactic steroids, which may produce clinical benefits. The SIRS trial assessed the hypothesis of whether methylprednisolone would reduce perioperative adverse events in high-risk patients undergoing cardiac surgery involving cardiopulmonary bypass.