RT Journal Article SR Electronic A1 Cunningham, Muriel T1 SYMPLICITY HTN-3 Trial: No Blood Pressure Reduction in Patients with Resistant Hypertension Treated with Renal Denervation JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 4 SP 14 OP 14 DO 10.1177/155989771404003 UL http://mdc.sagepub.com/content/14/4/14.1.abstract AB Previous research suggests that catheter-based renal artery denervation (RDN) reduces blood pressure in patients with resistant hypertension. This article presents the results of the Renal Denervation in Patients With Uncontrolled Hypertension trial [SYMPLICITY HTN-3; Bhatt DL et al. N Engl J Med 2014]. This was a large, prospective, randomized, blinded sham-controlled study conducted to assess the safety and efficacy of percutaneous RDN in patients with resistant hypertension.