PT - JOURNAL ARTICLE AU - Rizzo, Toni ED - Lublin, Fred D. TI - Controversies in Multiple Sclerosis Therapy DP - 2014 Jul 01 TA - MD Conference Express PG - 18--20 VI - 14 IP - 6 4099 - http://mdc.sagepub.com/content/14/6/18.short 4100 - http://mdc.sagepub.com/content/14/6/18.full AB - Considerable progress has been made in multiple sclerosis (MS) therapy in the 20 years since the first successful trial. Although several agents are now available for treating patients with MS, many issues remain regarding treatment of individual patients. This article discusses initiating MS therapy, and addressed the issues of switching and escalating therapy and of discontinuing therapy.