PT - JOURNAL ARTICLE AU - Nierengarten, Mary Beth ED - Mathew, Sanjay J. TI - Single-Dose Ketamine Associated with Rapid Improvement of Depressive Symptoms DP - 2014 Jul 01 TA - MD Conference Express PG - 17--18 VI - 14 IP - 8 4099 - http://mdc.sagepub.com/content/14/8/17.short 4100 - http://mdc.sagepub.com/content/14/8/17.full AB - Data from a randomized clinical trial show that patients with moderate to severe depressive symptoms treated with a single dose of ketamine show rapid improvement of depressive symptoms compared to patients treated with a psychoactive placebo control. This article discusses outcomes of the Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial [Murrough JA et al. Am J Psychiatry 2013].