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type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/advagg_css\/css__ce2QY63WIanKyr8eSq7eavr1XQRRmFD6ZSmwpyJi8lM__zXwFqpqmxrZOXXcd_TpBQpjuELbmIP9wBR5UuTDWAO4__YJWWMMdfCJuAFm5cUEp88OsodhO3ZA-2lzRfoBsSlk4.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-sageoa-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup\u0022 \u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 id=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022article fulltext-view \u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cdiv class=\u0022section abstract\u0022 id=\u0022abstract-1\u0022\u003E\u003Ch2\u003ESummary\u003C\/h2\u003E\n            \u003Cp id=\u0022p-1\u0022\u003EThis article discusses a poster with results of a study demonstrating that electroconvulsive therapy improves the symptoms of major depression more than pharmacological therapy alone [APA 2014 (poster NR5-06)].\u003C\/p\u003E\n         \u003C\/div\u003E\u003Cul class=\u0022kwd-group\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003EMood Disorders\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EPsychiatry Clinical Trials\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EPsychiatry\u003C\/li\u003E\u003C\/ul\u003E\u003Cul class=\u0022kwd-group clinical-trial\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003EMood Disorders\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EPsychiatry Clinical Trials\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EPsychiatry\u003C\/li\u003E\u003C\/ul\u003E\u003Cp id=\u0022p-2\u0022\u003ELucas Primo de Carvalho Alves, Hospital de Cl\u00ednicas de Porto Alegre, Porto Alegre, Brazil, presented a poster with results of a study demonstrating that electroconvulsive therapy (ECT) improves the symptoms of major depression more than pharmacological therapy alone [APA 2014 (poster NR5\u201306)].\u003C\/p\u003E\u003Cp id=\u0022p-3\u0022\u003EThe primary indication for use of ECT is in patients with depressive disorders who relapse despite the use of prescription medications. Although meta-analytical studies have demonstrated the efficacy of ECT in treatment of depressive disorders, it is challenging to successfully translate study results into clinical practice, particularly in patients with medical and psychiatric comorbid disease.\u003C\/p\u003E\u003Cp id=\u0022p-4\u0022\u003EWith this in mind, Alves and colleagues designed a study to evaluate the outcomes of ECT in severely depressed individuals admitted to a psychiatric inpatient facility.\u003C\/p\u003E\u003Cp id=\u0022p-5\u0022\u003ETo be included in the study, patients were required to be older than 18 years with a diagnosis of depression according to Mini International Neuropsychiatry Interview criteria. In total, 147 patients were enrolled and divided into 2 groups: ECT-treated (n=43; mean Hamilton Rating Scale for Depression [HAM-D] score, 25.05) and non-ECT-treated (n=104; mean HAM-D score, 21.61).\u003C\/p\u003E\u003Cp id=\u0022p-6\u0022\u003EPrimary outcomes were improvement in depression based on the HAM-D score; response (HAM-D improvement \u226550%); remission (HAM-D score \u22647); and duration of hospitalization.\u003C\/p\u003E\u003Cp id=\u0022p-7\u0022\u003EBased on mean HAM-D score from admission, symptoms of depression were significantly improved in the ECT-treated group (p=0.004; mean HAM-D score at discharge, 7.7) compared with the non-ECT-treated group (mean HAM-D score at discharge, 7.5).\u003C\/p\u003E\u003Cp id=\u0022p-8\u0022\u003EThe mean duration of hospitalization was significantly higher for patients in the ECT-treated group (p\u0026lt;0.001; 35.48 days), compared with those in the non-ECT-treated group (24.57 days).\u003C\/p\u003E\u003Cp id=\u0022p-9\u0022\u003EAlthough patients in the ECT-treated group had significantly higher depression scores at the time of admission to the study than those who did not receive ECT, at the time for discharge, patients in both groups had similar scores. Alves stated that this increased response rate highlights the efficacy and effectiveness of ECT in severely depressed patients.\u003C\/p\u003E\u003Cp id=\u0022p-10\u0022\u003EHe concluded that the longer hospitalizations in ECT-treated patients emphasizes the need for advance knowledge of clinical predictors of the response to ECT, to reduce the time between admission and the first session for patients who will benefit from ECT.\u003C\/p\u003E\u003Cul class=\u0022copyright-statement\u0022\u003E\u003Cli class=\u0022fn\u0022 id=\u0022copyright-statement-1\u0022\u003E\u00a9 2014 MD Conference Express\u00ae\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Ca href=\u0022http:\/\/mdc.sagepub.com\/content\/14\/8\/16.1.abstract\u0022 class=\u0022hw-link hw-link-article-abstract\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView Summary\u003C\/a\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_openurl.js?nzp8e2\u0022\u003E\u003C\/script\u003E\n\u003C\/body\u003E\u003C\/html\u003E"}