Summary

The connection between the brain and the heart is supported by the description of arrhythmias associated with the central nervous system. This article discusses noninvasive methods to assess sympathetic tone through sensors on the skin to assist with better describing and possibly even preventing these types of arrhythmic events. Other topics include the use of left cardiac sympathetic denervation to treat ischemic arrhythmias, and experimental data that support human clinical trials of device-based neuromodulation in patients with heart failure.