RT Journal Article
SR Electronic
A1 Nichols, Emma Hitt
T1 PARADIGM-HF: Rationale and Design
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 12
SP 11
OP 12
DO 10.1177/155989771412003
UL http://mdc.sagepub.com/content/14/12/11.abstract
AB The Multicenter, Randomized, Double-blind, Parallel Group, Active-controlled Study to Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure and Reduced Ejection Fraction [PARADIGM-HF; NCT01035255] is the largest trial ever conducted with patients with heart failure with a reduced left ventricular ejection fraction and was designed to replace the current standard of care. This article discusses the rationale and design of the PARADIGM-HF trial.