RT Journal Article
SR Electronic
A1 Kuznar, Wayne
T1 Notable Developments in Genomic Profiling Have Enhanced Personalized Cancer Care
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 14
SP 29
OP 31
DO 10.1177/155989771414017
UL http://mdc.sagepub.com/content/14/14/29.abstract
AB Tumor genomic profiling in clinical studies and the integration of tumor genomics into clinical practice are rapidly becoming the standard of care. This article discusses methods to apply genomics to guide clinical investigation, next-generation sequencing, how homologous recombination acts as a target and as a predictive and prognostic biomarker, and the therapeutic dissection of lung cancer.