PT - JOURNAL ARTICLE AU - Kuznar, Wayne ED - Workman, Paul TI - Notable Developments in Genomic Profiling Have Enhanced Personalized Cancer Care DP - 2014 Aug 01 TA - MD Conference Express PG - 29--31 VI - 14 IP - 14 4099 - http://mdc.sagepub.com/content/14/14/29.short 4100 - http://mdc.sagepub.com/content/14/14/29.full AB - Tumor genomic profiling in clinical studies and the integration of tumor genomics into clinical practice are rapidly becoming the standard of care. This article discusses methods to apply genomics to guide clinical investigation, next-generation sequencing, how homologous recombination acts as a target and as a predictive and prognostic biomarker, and the therapeutic dissection of lung cancer.