RT Journal Article
SR Electronic
A1 Rizzo, Toni
T1 DBS Improves FOG in Patients with PD
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 15
SP 14
OP 15
DO 10.1177/155989771415005
UL http://mdc.sagepub.com/content/14/15/14.abstract
AB High-frequency deep brain stimulation (DBS) is effective for relief of Parkinson's disease (PD) symptoms. However, studies on the effect of subthalamic nucleus DBS (STN-DBS) on freezing of gait (FOG) have reported inconsistent results, with some suggesting that STN-DBS alleviates FOG [Davis JT et al. Clin Neurol Neurosurg 2006] and others reporting worsening of gait and balance [van Neunen BFL et al. Mov Disord 2008; Krack P et al. N Engl J Med 2003]. This article discusses the the Vercise Implantable Stimulator for Treating Parkinson's Disease trial [VANTAGE; NCT01221948].