RT Journal Article SR Electronic A1 Rizzo, Toni T1 The Parkinson's Journey: From Drug Discovery to Treatment of Early and Advancing Disease JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 15 SP 4 OP 6 DO 10.1177/155989771415001 UL http://mdc.sagepub.com/content/14/15/4.abstract AB Efforts to find a treatment for Parkinson's disease (PD) began in the mid-1950s with the discovery of levodopa (L-dopa). Since then, advancements in treatment have included a variety of different modes of L-dopa administration as well as the development of other medical therapies, continuous infusions, and deep brain stimulation. This discusses the L-dopa story and treatment strategies for early and late PD.