RT Journal Article SR Electronic A1 Vinall, Maria T1 Using the Legacy Effect to Improve Patient Outcomes JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 19 SP 21 OP 22 DO 10.1177/155989771419014 UL http://mdc.sagepub.com/content/14/19/21.abstract AB Among individuals with diabetes, early intensive glycemic control is associated with long-term benefits 10 or more years later (ie, the legacy effect) [Holman RR et al. N Engl J Med 2008]. This article discusses the clinical implications of the legacy effect and the lag time before additional antihyperglycemic agents are added.