PT  - JOURNAL ARTICLE
AU  - Hoyle, Brian
ED  - Fujita, Toshiro
TI  - Mechanisms of Salt-Sensitive Hypertension
DP  - 2014 Sep 01
TA  - MD Conference Express
PG  - 4--5
VI  - 14
IP  - 18
4099  - http://mdc.sagepub.com/content/14/18/4.short
4100  - http://mdc.sagepub.com/content/14/18/4.full
AB  - This article discusses the mechanisms of salt-sensitive hypertension. The link between salt intake and hypertension is not a recent discovery but, rather, has been known for a half-century on the basis of studies conducted worldwide. Subjects with hypertension can be classified as salt-insensitive and salt-sensitive. It is beginning to be understood that salt sensitivity can be modulated by multiple mechanisms, including the renal sympathetic nervous system, the mineralocorticoid receptor, and aldosterone.