Summary

In patients with intra-atrial conduction delay to the posterior triangle of Koch, pacing the interatrial septum (IAS) may play a role in preventing permanent or persistent atrial fibrillation (AF). This article presents data from the Electrophysiology-Guided Pacing Site Selection study, a prospective, active-controlled, randomized, multicenter study that assessed the efficacy of atrial pacing at the IAS versus the right atrial appendage to prevent persistent or permanent AF in patients with sinus node disease [Verlato R et al. Circ Arrhythm Electrophysiol 2011].