RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 Neonatal Exposure to BPA Affects Puberty Onset in Rats
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 20
SP 9
OP 10
DO 10.1177/155989771420004
UL http://mdc.sagepub.com/content/14/20/9.abstract
AB Bisphenol A (BPA) is an industrial chemical used to make polycarbonate—a hard, clear plastic used in many consumer products. Endocrine-disrupting effects of low BPA doses in the microgram range are a matter of controversy. However, this article reports that an injection of a very low dose (25 ng/kg/day) of BPA into neonatal rats delayed puberty, slowed down gonadotropin-releasing hormone secretion, and changed hypothalamic RNA expression.