PT  - JOURNAL ARTICLE
AU  - Vinall, Maria
ED  - Bourguignon, Jean-Pierre
TI  - Neonatal Exposure to BPA Affects Puberty Onset in Rats
DP  - 2014 Nov 01
TA  - MD Conference Express
PG  - 9--10
VI  - 14
IP  - 20
4099  - http://mdc.sagepub.com/content/14/20/9.short
4100  - http://mdc.sagepub.com/content/14/20/9.full
AB  - Bisphenol A (BPA) is an industrial chemical used to make polycarbonate—a hard, clear plastic used in many consumer products. Endocrine-disrupting effects of low BPA doses in the microgram range are a matter of controversy. However, this article reports that an injection of a very low dose (25 ng/kg/day) of BPA into neonatal rats delayed puberty, slowed down gonadotropin-releasing hormone secretion, and changed hypothalamic RNA expression.