New Analysis of CRYSTAL Results Supports Patient Selection According to RAS Mutation Status to Maximize Benefit from CET Therapy

Summary

The randomized Phase 3 Cetuximab Combined With Irinotecan in First-Line Therapy for Metastatic Colorectal Cancer trial [CRYSTAL; Van Cutsem E et al. N Engl J Med 2009] investigated the efficacy and safety of cetuximab combined with a simplified regimen of leucovorin–5-flourouracil—irinotecan (FOLFIRI) for the initial treatment of metastatic colorectal cancer.

  • Oncology Clinical Trials
  • Gastrointestinal Cancers
  • Oncology Clinical Trials
  • Gastrointestinal Cancers
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