RT Journal Article
SR Electronic
A1 Hoyle, Brian
T1 Beneficial Effects of Once-Daily Edoxaban in Patients with AF
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 24
SP 11
OP 13
DO 10.1177/155989771424004
UL http://mdc.sagepub.com/content/14/24/11.abstract
AB This article reports the results of the Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation—TIMI 48 trial [ENGAGE AF-TIMI 48]. This randomized, double-blind, double-dummy trial of 21,105 patients demonstrated the efficacy and safety of a once-daily regimen of the oral anticoagulant edoxaban in treatment of atrial fibrillation (AF). The primary trial results have been published [Giugliano RP et al. N Engl J Med 2013].