RT Journal Article
SR Electronic
A1 Bittner, Dennis
T1 Exenatide Increases Glucose Uptake in Brain Areas Involved in Glucose Homeostasis and Food Intake
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 32
SP 19
OP 19
DO 10.1177/155989771432012
UL http://mdc.sagepub.com/content/14/32/19.abstract
AB GLP-1 is secreted in response to food ingestion, although the action of glucagon-like peptide–1 on brain glucose metabolism has been hypothesized but has not yet been established. This article presents results from the Effect of Exenatide on Brain, Adipose Tissue, Pancreas, and Liver Function study [NCT01588418], a phase 4 clinical trial that aimed to evaluate the effect of a single injection of exenatide (a GLP-1 agonist) on cerebral glucose metabolism during an oral glucose tolerance test.