RT Journal Article
SR Electronic
A1 Vinall, Phil
T1 Systemic Treatment for Advanced NSCLC
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 36
SP 29
OP 30
DO 10.1177/155989771436022
UL http://mdc.sagepub.com/content/14/36/29.abstract
AB The recent understanding of the relation between the cancer cell and the immune system includes a knowledge of how the cancer cell produces proteins that prevent the immune system from recognizing and killing the cancer cell, as well as the identification of a series of inhibitory receptors, activating receptors, and other pathways. This understanding is advancing the field of systemic immune therapy for oncology. Non-small cell lung cancer (NSCLC) is a heterogeneous disease with numerous driver mutations. This article discusses new insights into immune privilege, improved diagnosis, as well as the need for drugs to overcome secondary resistance to systemic treatment.