PT  - JOURNAL ARTICLE
AU  - Vinall, Phil
ED  - O'Byrne, Ken J.
TI  - Systemic Treatment for Advanced NSCLC
DP  - 2014 Dec 01
TA  - MD Conference Express
PG  - 29--30
VI  - 14
IP  - 36
4099  - http://mdc.sagepub.com/content/14/36/29.short
4100  - http://mdc.sagepub.com/content/14/36/29.full
AB  - The recent understanding of the relation between the cancer cell and the immune system includes a knowledge of how the cancer cell produces proteins that prevent the immune system from recognizing and killing the cancer cell, as well as the identification of a series of inhibitory receptors, activating receptors, and other pathways. This understanding is advancing the field of systemic immune therapy for oncology. Non-small cell lung cancer (NSCLC) is a heterogeneous disease with numerous driver mutations. This article discusses new insights into immune privilege, improved diagnosis, as well as the need for drugs to overcome secondary resistance to systemic treatment.