RT Journal Article
SR Electronic
A1 Parry, Nicola
T1 Interim Safety Analysis of nP in High-Risk Early Breast Cancer
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 36
SP 12
OP 13
DO 10.1177/155989771436008
UL http://mdc.sagepub.com/content/14/36/12.abstract
AB Combination chemotherapy requires compromises in drug dosage and treatment intervals because of acute and cumulative toxicities. The sequential use of monotherapies, however, allows for the use of high doses of single agents and dose-dense treatment intervals, and such regimens have been very effective in cases of early breast cancer with high risk of recurrence. This article discusses data from the first interim safety analysis of the Study of Nab-Paclitaxel in High-Risk Early Breast Cancer [GAIN2; NCT01690702], demonstrating acceptable initial toxicity profiles.