Summary

This article reviews the main data regarding ticagrelor, prasugrel, and clopidogrel therapy in patients with ST-segment elevation myocardial infarction (STEMI). Additional topics include new evidence regarding the timing of antiplatelet loading, managing antiplatelet therapy in patients undergoing CABG surgery, as well as new strategies for managing atrial fibrillation and concomitant coronary artery disease and acute coronary syndromes.