Summary

About 20% of patients presenting to the emergency department with acute myocardial infarction (AMI) receive an inconsistent diagnosis when using the approved clinical decision values (CDVs) for cardiac troponin (cTn). This article discusses results of a study designed to quantify inconsistencies in the diagnosis of AMI related to limitations in the definition of CDVs for high-sensitivity cTn assays (cardiac troponin T, hs-cTnT; and troponin I, hs-cTnI).