PT - JOURNAL ARTICLE AU - Nierengarten, Mary Beth ED - Bansback, Nick TI - Triple Therapy More Cost-effective than Biologic First in Patients Who Fail MTX DP - 2014 01 TA - MD Conference Express PG - 13--14 VI - 14 IP - 51 4099 - http://mdc.sagepub.com/content/14/51/13.short 4100 - http://mdc.sagepub.com/content/14/51/13.full AB - For patients with rheumatoid arthritis (RA) who fail methotrexate (MTX), using a biologic instead of triple therapy first is not a cost-effective use of health care resources due to the large additional costs for very small benefits. This article presents the results of a randomized noninferiority trial that compared the cost-effectiveness of treating patients who fail MTX with a biologic first or adding triple therapy followed by a biologic.