PT  - JOURNAL ARTICLE
AU  - Kuznar, Wayne
ED  - Strand, Vibeke
TI  - GR Agonist Improves Responses in RA
DP  - 2014  01
TA  - MD Conference Express
PG  - 8--9
VI  - 14
IP  - 51
4099  - http://mdc.sagepub.com/content/14/51/8.short
4100  - http://mdc.sagepub.com/content/14/51/8.full
AB  - The glucocorticoid receptor (GR) regulates genes that control development and metabolism and the immune response. A dissociated agonist of the glucocorticoid receptor (DAGR) is a nonsteroidal ligand of the GR that has both partial agonist and antagonistic properties. This article discusses a phase 2 trial that compared response rates between a DAGR and prednisone in patients with rheumatoid arthritis.