RT Journal Article
SR Electronic
A1 Mosley, Mary
T1 ENGAGE AF-TIMI 48: Edoxaban Safe and Effective in Elderly Patients with AF
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 52
SP 25
OP 26
DO 10.1177/155989771452017
UL http://mdc.sagepub.com/content/14/52/25.abstract
AB Atrial fibrillation (AF) becomes more common with increasing age. Data from an unpublished new analysis of the Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation [ENGAGE AF-TIMI 48] support edoxaban as an alternative treatment to warfarin in elderly patients who require anticoagulation therapy. This article discusses a prespecified analysis that evaluated the association of age on study outcomes and the efficacy and safety of edoxaban relative to warfarin in the elderly with AF.