PT - JOURNAL ARTICLE AU - Nichols, Emma Hitt ED - Cannon, Christopher P. TI - Ezetimibe Plus Statin Reduces CV Events after ACS DP - 2014 01 TA - MD Conference Express PG - 17--18 VI - 14 IP - 52 4099 - http://mdc.sagepub.com/content/14/52/17.short 4100 - http://mdc.sagepub.com/content/14/52/17.full AB - Statins have been demonstrated to reduce morbidity and mortality; however, adding other lipid-modifying therapies to statin treatment has not demonstrated a clear benefit. This article presents data from the Improved Reduction of Outcomes: Vytorin (Ezetimibe/Simvastatin) Efficacy International Trial [IMPROVE-IT; NCT00202878]. The purpose of the IMPROVE-IT trial was to evaluate the clinical benefit of combination therapy with ezetimibe plus simvastatin compared with simvastatin monotherapy in lowering LDL-C levels.