RT Journal Article SR Electronic A1 Nichols, Emma Hitt T1 Alirocumab Has Greater Reduction of LDL-C Than Ezetimibe in Patients with Statin Intolerance JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 52 SP 16 OP 17 DO 10.1177/155989771452008 UL http://mdc.sagepub.com/content/14/52/16.abstract AB In clinical practice, up to 25% of patients are statin intolerant as a result of symptoms and abnormalities in biomarkers. This article discusses results from the Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular Risk, Who Are Intolerant to Statins [Odyssey Alternative; NCT01709513]. These trials compared statin intolerant patients who were treated with alirocumab versus ezetimibe.