Summary

The Is There a Life for Drug Eluting Stent (DES) After Discontinuation of Clopidogrel trial [ITALIC/ITALICplus] was a large, prospective, open-label randomized trial conducted at 55 sites in Europe and the Middle East, and is discussed in this article. The objective of the trial was to determine if 6 months of dual antiplatelet therapy (DAPT) was noninferior to 24 months of DAPT following DES placement.