AC and Weekly Paclitaxel Improve Outcomes in TNBC

Summary

This article presents the 10-year results of a study comparing taxane type and schedule as a component of adjuvant chemotherapy in localized breast cancer. When administered after doxorubicin-cyclophosphamide, weekly paclitaxel and every-3-weeks docetaxel significantly improved outcomes in the entire study population, while weekly paclitaxel improved outcomes in triple-negative breast cancer.

  • adjuvant therapy
  • combination treatment
  • axillary node positive
  • disease-free survival
  • doxorubicin
  • cyclophosphamide
  • paclitaxel
  • A Phase 3 Study of Doxorubicin-Cyclophosphamide Followed by Paclitaxel or Docetaxel Given Weekly or Every 3 Weeks in Patients With Axillary Node-Positive Breast Cancer
  • E1199
  • BC
  • NCT00004125
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