PT - JOURNAL ARTICLE AU - Kuznar, Wayne ED - McInnes, Iain B. TI - Inhibitor of Interleukins 12 and 23 Slows Joint Destruction in Psoriatic Arthritis DP - 2013 Feb 01 TA - MD Conference Express PG - 15--16 VI - 13 IP - 18 4099 - http://mdc.sagepub.com/content/13/18/15.short 4100 - http://mdc.sagepub.com/content/13/18/15.full AB - A prespecified integrated analysis of two Phase 3 clinical trials demonstrates that the monoclonal antibody ustekinumab reduces radiographic progression of joint disease in patients with active psoriatic arthritis. This article presents the integrated analysis of the two Phase 3 Multicenter, Randomised, Double-Blind, Placebo-Controlled Trials of Ustekinumab, a Fully Human Anti-IL-12/23p40 Monoclonal Antibody, Administered Subcutaneously, in Subjects With Active Psoriasis Arthritis [PSUMMIT I and II; NCT01009086; NCT01077362].