RT Journal Article SR Electronic A1 Nichols, Emma Hitt T1 Addition of AMPLATZER PFO Occluder to Medical Therapy is Beneficial in Patients with Cryptogenic Stroke and PFO JF MD Conference Express YR 2013 FD SAGE Publications VO 13 IS 1 SP 18 OP 19 DO 10.1177/155989771301005 UL http://mdc.sagepub.com/content/13/1/18.abstract AB Cryptogenic stroke remains a major challenge for clinicians taking care of patients who have had strokes. Patent foramen ovale (PFO) is a contributor to cryptogenic stroke due to paradoxical embolism [Furlan AJ et al. N Engl J Med 2012], but the optimal management strategy for PFO has yet to be defined [Kitsios GD et al. Stroke 2012]. This article reports the results of a follow-up analysis of the RESPECT PFO Clinical Trial [RESPECT; NCT00465270] to characterize the qualifying and endpoint ischemic strokes.