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- Figure 1.
EVEREST Objectives
Reproduced with permission frm MA Konstam, MD.
- Figure 2.
Chronic PDE5 Inhibition Improves Left Ventricular Systolic Dysfunction
LVEDV=left ventricular end diastolic volume; LVMI=left ventricular myocardial infarction; LVEF-left ventricular ejection fraction; PDE-5=phosphodiesterase type 5.
*p<0.01 vs placebo; #p<0.01 vs baseline.
Reproduced from Guazzi M et al. PDE5 Inhibition With Sildenafil Improves Left Ventricular Diastolic Function, Cardiac Geometry, and Clinical Status in Patients With Stable Systolic Heart Failure: Results of a 1-Year, Prospective, Randomized, Placebo-Controlled Study. Circulation Heart Failure 2011;4(1)8–17.
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