PT - JOURNAL ARTICLE AU - Vinall, Phil ED - Toso, Anna TI - High-Dose Rosuvastatin Reduces Contrast-Induced Nephropathy DP - 2013 May 01 TA - MD Conference Express PG - 14--15 VI - 13 IP - 2 4099 - http://mdc.sagepub.com/content/13/2/14.short 4100 - http://mdc.sagepub.com/content/13/2/14.full AB - Among statin-naïve patients with non-ST-segment elevation acute coronary syndrome managed with an early invasive strategy, pretreatment with high-dose rosuvastatin was associated with a significant reduction in the incidence of contrast-induced acute kidney injury. In addition, pretreatment with rosuvastatin was also associated with a reduction in adverse clinical events at 30 days compared with placebo. This article presents the results of the Protective Effect of Rosuvastatin and Antiplatelet Therapy on Contrast-Induced Acute Kidney Injury and Myocardial Damage in Patients With Acute Coronary Syndrome study [PRATO-ACS; NCT01185938].