PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Andtbacka, Robert H. I. TI - OPTiM Study Results DP - 2013 Aug 01 TA - MD Conference Express PG - 17--17 VI - 13 IP - 6 4099 - http://mdc.sagepub.com/content/13/6/17.1.short 4100 - http://mdc.sagepub.com/content/13/6/17.1.full AB - Results from the Efficacy and Safety Study of OncoVEX Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Compared to GM-CSF in Melanoma [OPTiM; NCT00769704; Andtbacka RHI et al. J Clin Oncol 2013 (suppl; abstr LBA9008)] showed that a genetically modified version of herpes simplex virus type 1 (talimogene laherparepvec), is safe and improves durable response rate in patients with unresectable stage IIIB-IV melanoma.