Summary

The Telemonitoring and Self-Management in the Control of Hypertension trial [TASMINH2], a large study of patients with hypertension, found that those randomized to self-management had significantly lower blood pressure (BP) than controls [McManus RJ et al. Lancet 2010]. Subgroup analyses from TASMINH2 suggested a smaller treatment effect in higher risk patients. The purpose of the subsequent Targets and Self management for the Control of Blood Pressure in Stroke and Other At-risk Groups trial [TASMIN-SR; ISRCTN87171227] was to determine if self-management, consisting of self-monitoring with self-titration of antihypertensives, effectively lowers BP in patients with high-risk conditions such as stroke and diabetes [O'Brien C et al. BMC Cardiovasc Disord 2013].