RT Journal Article SR Electronic A1 Parry, Nicola T1 Dual Chamber ICD Therapy Associated with Fewer Inappropriate Shocks JF MD Conference Express YR 2013 FD SAGE Publications VO 13 IS 12 SP 19 OP 20 DO 10.1177/155989771312009 UL http://mdc.sagepub.com/content/13/12/19.abstract AB This article presents data from an international multicenter study, demonstrating that patients with dual-chamber (DC) implantable cardioverter defibrillators (ICDs) experienced a significantly lower incidence of inappropriate shocks compared with those with single-chamber devices, with no difference in all-cause mortality between the two groups. The Optimal Anti-tachycardia Therapy in ICD Patients Without Pacing Indications study [OPTION; NCT00729703] was designed to test the hypothesis that DC ICD therapy with specific device-based algorithms would reduce the rate of inappropriate shocks without affecting morbidity and mortality by ventricular pacing.