Summary

This article presents data from an international multicenter study, demonstrating that patients with dual-chamber (DC) implantable cardioverter defibrillators (ICDs) experienced a significantly lower incidence of inappropriate shocks compared with those with single-chamber devices, with no difference in all-cause mortality between the two groups. The Optimal Anti-tachycardia Therapy in ICD Patients Without Pacing Indications study [OPTION; NCT00729703] was designed to test the hypothesis that DC ICD therapy with specific device-based algorithms would reduce the rate of inappropriate shocks without affecting morbidity and mortality by ventricular pacing.