RT Journal Article
SR Electronic
A1 Buckley, Rita
T1 Complement Inactive in E. coli Shiga Toxin-Producing Diseases
JF MD Conference Express
YR 2013
FD SAGE Publications
VO 13
IS 13
SP 16
OP 17
DO 10.1177/155989771313009
UL http://mdc.sagepub.com/content/13/13/16.abstract
AB In a nonhuman primate model of hemolytic uremic syndrome, complement was not activated despite clear microvascular thrombosis and cellular injury. Complement is an important immune defense mechanism. This article presents outcomes from a study on the role of complement in HUS and thrombotic microangiography induced by Escherichia coli (E. coli) Shiga toxins.