PT - JOURNAL ARTICLE AU - Kuznar, Wayne ED - Baglin, Trevor TI - In Search of the Holy Grail of Anticoagulant Therapy DP - 2013 Sep 01 TA - MD Conference Express PG - 12--13 VI - 13 IP - 13 4099 - http://mdc.sagepub.com/content/13/13/12.short 4100 - http://mdc.sagepub.com/content/13/13/12.full AB - The trade-off between antithrombotic effect and bleeding hinders the efficacy of current anticoagulant therapy. An antibody in development has demonstrated dissociation of the antithrombotic effect from the bleeding effect in preclinical studies, showing promise as a revolutionary drug for the treatment of thrombosis.