RT Journal Article SR Electronic A1 Vinall, Maria T1 Apixaban is an Effective Replacement for Conventional Anticoagulation Therapy JF MD Conference Express YR 2013 FD SAGE Publications VO 13 IS 13 SP 11 OP 12 DO 10.1177/155989771313004 UL http://mdc.sagepub.com/content/13/13/11.abstract AB Apixaban, an oral factor Xa inhibitor, is noninferior to enoxaparin plus warfarin for the treatment of acute symptomatic proximal deep vein thrombosis and pulmonary embolism, and is associated with significantly less bleeding compared with conventional therapy. Administered in fixed doses, apixaban may simplify the treatment of acute venous thromboembolism. This article presents the results of the Efficacy and Safety Study of Apixaban for the Treatment of Deep Vein Thrombosis or Pulmonary Embolism [AMPLIFY; NCT00643201].